Words similar to synergism
Example sentences for: synergism
How can you use “synergism” in a sentence? Here are some example sentences to help you improve your vocabulary:
A similar synergism was observed for virucidal activity against HIV-1 IIIB (Fig.
Since HIV-1 can bind CAP and sCD4 simultaneously, and the binding of CAP is enhanced in the presence of sCD4, it was of interest to determine whether these two ligands act on HIV-1 cooperatively, resulting in synergism of their antiviral effects.
Earlier studies describing the underlying molecular mechanisms involved in the HIV-1 inhibitory effect of the candidate microbicide CAP indicated that this compound remains bound to HIV-1, impairing virus infectivity by blockade of binding sites for cellular coreceptors CXCR4 and CCR5 [ 8 ] . Results reported here further extend these findings and show that: 1) there is synergism between sCD4 and CAP for inhibition of virus infectivity; 2) CAP binding to HIV-1 leads to conformational changes in viral envelope glycoproteins resulting in the expression of functionally inert six-helix bundle structures.
Although the underlying mechanism of such synergism is unclear, it is of great interest to combine the two drugs in clinical lung cancer patients to see if the synergy of the two drugs exists under the physiological conditions.
Author 3 SJ developed monoclonal antibody NC-1 and was involved in studies on the gp41 six helix bundles and on synergism between CAP and sCD4 for inhibition of HIV-1 infectivity.