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Example sentences for: synergistic
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Experiments with Arr dsRNAi clearly establish a requirement for endogenous Arr to generate the synergistic response to exogenous Wg plus DFz2 in S2 cells (Figure 2).
At the present time, the T3197C nucleotide substitution is considered a polymorphism and it is not thought to have pathogenic significance by itself [ 31 ] . Although most pathogenic mutations are heteroplasmic, many homoplasmic mutations have been reported to have synergistic effects in the presence of other primary mutations [ 32 33 ] . The only difference in mtDNA between the affected child and the asymptomatic mother is the A189G mutation in the hypervariable D-loop region.
We conclude that SAR, PR-1 induction and PR-5 induction are regulated in parallel by the two pathways we have previously delineated [ 4 ] , but the effects of these pathways are additive rather than obligatorily synergistic.
Taken together, these two types of studies are largely consistent with the main conclusions of the present paper, that synergistic interactions do not generally dominate the fitness function and compensatory mutations are common.
Even when the average neutrality decays quickly as one moves away from the reference sequence, the corresponding value of β indicates at most a very slight tendency toward synergistic epistasis.