Words similar to suppressors
Example sentences for: suppressors
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Other mechanisms that may participate in the RU 486-induced inhibition of hepatic apoptosis include the fact that this compound blocks the inhibitory effect of glucocorticoids on suppressors of cytokine signalling in the liver [ 8 ] . This family of proteins is induced by growth hormones and cytokines, and is strongly repressed in vivo by glucocorticoids [ 8 ] . Up-regulation of these proteins by RU 486 [ 8 ] , coupled with significant increase in hepatic TNFα level found in animals treated with RU 486 [ 12 ] , may contribute to the inhibition of apoptosis observed in our study (Fig 1B).
These include transcription factors (panel A), cytokines, growth factors, and their receptors (panel B), proteases, matrix proteins, and adhesion molecules (panel C), as well as signaling intermediates and tumor suppressors (panel D).
At least cell cycle related proteins, either suppressors or facilitators, and growth factors and cytokines produced by stromal cells [ 1 46 47 48 49 ] should be considered in addition to the promitotic effect of E2 mediated via ERα.
The requirement for tight regulation, easy titration and minimal background expression is particularly important in the study of genes such as tumor suppressors or cell cycle regulatory genes for which cell lines stably expressing the product can rarely be made.
The rewiring recommendation from the National Transportation Safety Board, accompanied by the further suggestion that surge suppressors be put on wires going into fuel tanks, shows, says the NYT , how far investigators have come in their understanding of the TWA crash.
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