Example sentences for: suppress

How can you use “suppress” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, advanced human tumors show increased levels of TGF-β expression [ 42, 43, 44], and TGF-βs are known to suppress the immunosurveillance system, to enhance angiogenesis, invasion and metastasis, and to increase drug resistance [ 45, 46, 47, 48].

  • Likewise, in the F2 progeny, L91' continued to suppress the endogene silencing by E82 (Table 2; Fig.

  • In his effort to build nationalism across Turkey in the 1920s, Atatürk instituted a campaign to suppress Kurdish identity that continues today.

  • The use of the Freikorps to suppress the Spartacists was to haunt the Weimar Republic.

  • COX-2 is an inducible enzyme upregulated in inflammatory states [ 20 21 ] . Notably, many NSCLC and what have been characterized as "premalignant" lung lesions have been shown to constitutively express the COX-2 enzyme and produce prostaglandin E-2 (PGE-2), the primary product of the COX-2 pathway [ 22 23 24 25 26 ] . Importantly, PGE-2 production by tumor cells has been linked to tumor-induced immunosuppression in NSCLC [ 2 3 4 5 ] . PGE-2 has been shown to directly suppress T cell mediated immunity, the primary effector against tumor cells, at a variety of levels [ 2 3 4 5 6 7 ] . Further, PGE-2 has been shown to induce the IL10 in mononuclear cells [ 4 5 ] . IL10 is a prominent immunosuppressive cytokine that may have a dominant role in preventing innate antitumor responses in the NSCLC environment [ 2 3 4 5 ] , [ 8 9 10 11 12 13 14 15 16 17 18 19 ] . Among myriad suppressive effects on T cells and antigen presenting cells, IL10 is known to inhibit IL12 production [ 14 15 16 17 18 ] . IL12 plays a key role in the initiation and potentiation of cellular immune responses and alteration of the IL12 producing function in circulating mononuclear phagocytes may be a critical factor in suppressed T cell immunity to NSCLC [ 27 28 ] .


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