Words similar to suppress
Example sentences for: suppress
How can you use “suppress” in a sentence? Here are some example sentences to help you improve your vocabulary:
Indeed, in a recent phase II clinical trial, 9% of MS patients given an altered peptide ligand (APL) of a myelin basic protein epitope developed immediate hypersensitivity reactions after multiple injections of the APL [ 29 ] . Thus, it would appear that great care must be taken when injecting preparations of putative "tolerogens" in attempts to suppress T H 1-mediated autoimmune diseases.
To address the relationship of Nrg1 to both complexes and to compare it to Mig1, we tested the abilities of nrg1Δ and mig1Δ to suppress the Gal -, Suc -, and Raf -phenotypes of mutations in SNF1 and SWI/SNF genes.
These studies indicate that PP5 mediated suppression of GR-function arises from the ability of PP5 to suppress the nuclear accumulation of GRs.
The current data is consistent with PP5 acting to suppress the nuclear import of GRs.
In some circumstances, CD4 +and CD8 +T cells were rendered inactive in tumor-bearing hosts [ 8 ] . The inactivation of CD4 +T cells has been attributed either to the tumor cells themselves or to bone marrow-derived cells [ 9 10 11 ] , whereas antigen ignorance or loss of memory have been postulated to underlay that of CD8 +T cells [ 12 13 ] . Other studies have suggested that tumor cells can secrete immunosuppressive factors such as TGF-β or express Fas ligand to induce apoptosis of infiltrating lymphocytes [ 14 15 16 ] . Furthermore, the tumor vasculature appears to be quite different from normal blood vessels, in terms of structural organization, interstitial pressure, and flow patterns [ 17 ] , and in reduced lymphocyte and natural killer cell homing and adhesion [ 18 19 20 21 ] . The existence of significant barriers to effective immunological destruction is further illustrated by a mouse model of concurrent multistage tumorigenesis and anti-oncogene autoimmunity, wherein progenitor dysplastic lesions are infiltrated and disrupted, while solid tumors are not [ 22 ] . The hypothesis is that the microenvironment of certain types of solid tumor can serve to locally suppress T cell infiltration.
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