Example sentences for: suppresses

How can you use “suppresses” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Released NF-κB dimers then translocate to the nucleus, bind to its cognate DNA elements, and induce the expression of target genes [ 23 24 25 ] . Activated, nuclear translocated, NF-κB transcription factor has been documented in the mouse embryo from the 1-cell stage onward [ 26 27 ] . Activated NF-κB translocation into the nucleus, directly or indirectly, effects the transcriptional control of over 150 target genes [ 28 ] . NF-κB enhances cell proliferation by stimulating the expression of cytokines such as TNF, IL-1, IL-2, IL-6, and IL-8, among others [ 28 29 ] ; NF-κB inhibits apoptosis by inducing TRAF and clAP expression which suppresses Caspase 8 activation [ 30 ] , and by inhibition of p53 transactivation [ 31 32 ] .

  • Thus, the precise molecular mechanism by which PP5 suppresses the nuclear accumulation of GR remains to be elucidated.

  • Consistent with a role in glucose repression, an nrg1Δ mutation suppresses the defects of a snf1Δ mutant.

  • In hamsters, rats and mice, increases and decreases in bile acid absorption at the brush border membrane are mediated by an up- or down-regulation in IBAT gene transcription [ 33 34 ] . In several rodent species including mice, regulation of IBAT is clearly dependent on intraluminal bile acid concentrations and occurs via a negative feedback mechanism [ 33 34 35 ] . Feeding of bile acids suppresses transcription of IBAT mRNA and reduces IBAT protein abundance; feeding of the bile acid binder cholestyramine has the opposite effect.

  • The battle comes between cases in which information in a higher cortical area, acting as prior information, boosts activities in a lower cortical area, and cases of predictive coding, in which the higher cortical area informs the lower cortical area about what it already knows and therefore suppresses the information that the lower area would otherwise just repeat up the hierarchy.


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