Words similar to suppressor
Example sentences for: suppressor
How can you use “suppressor” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cytogenetic and molecular genetic analyses have identified the short arm of chromosome 5, 5p, as frequently affected by duplications and deletions in a high proportion of CCs [ 3 4 5 6 ] . These findings suggest the presence of positively regulated amplified oncogenes and negatively regulated tumor suppressor genes (TSGs) on this chromosomal arm.
Since RARB functions as a tumor suppressor gene and its chemopreventive effects are purely based on retinoid induced reactivation, the patients that received radiation therapy will have no effect on these tumors.
A mutation was considered an enhancer if the wings were significantly shorter and a suppressor if they were clearly longer.
The functions of Boi1/Boi2 appear to be linked to those of Cdc42 and Rho3, which are Rho-type GTPases that are important for polarized cell growth [ 4 5 6 7 8 9 ] . Boi1 and Boi2 display two-hybrid interactions with both wild-type and mutationally activated Cdc42 but not with a mutant version of Cdc42 that is predicted to be impaired in the ability to bind nucleotide, suggesting that Boi1 and Boi2 may associate with the GTP-bound ("active") form of Cdc42 [ 1 ] . Further evidence that some function of Boi1 is linked to that of Cdc42 is that overexpression of Boi1 inhibits bud emergence and that this inhibition can be suppressed by overexpression of Cdc42 [ 1 2 ] . RHO3 can serve as a multicopy suppressor of the lethality caused by deletion of BOI1 and BOI2 [ 1 2 ] . These findings are consistent with the possibilities that Boi1 and Boi2 are targets of Cdc42 that promote cell growth in a manner that is regulated by Rho3.
The TGF-β system has tumor suppressor activity, and loss of TGF-β response is associated with advanced disease in many human tumor types, including the breast [ 9, 10].
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