Words similar to suppressive

Example sentences for: suppressive

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Study-defined criteria for therapy failure of a previously suppressive regimen were met by 4/21 patients in the continuous therapy/single interruption arm (patients S37, S47, S52, and S59) in association with self-reported nonadherence to therapy and detection of resistance mutations in phase I, as listed in Table 2. One patient in the repeated interruptions arm (1/21; patient S56) failed therapy after 20 wk following the third TI by maintaining a viral load between 50 and 999 copies/ml in the presence of previously undetected resistance mutations.
However, no impact on cell growth in culture was found in clones with high constitutive Syk activity, nor was the growth suppressive effect of anti-IgM treatment enhanced (Figure 7A).
The initial experiments were performed to confirm our earlier finding that RGS3 suppressed GnRH-stimulated IP 3 production in COS-1 cells [ 9 ] and to test a truncated form of RGS3, RGS3T (RGS3 314-519) [ 24 ] for suppressive activity in the same assay (Fig.
This is in contrast to the results observed on matrix synthesis in chondrocytes in culture, where TGF-β1 was able to stimulate significant new matrix synthesis as well as overcome the suppressive effects of IL-1β on matrix metabolism [ 21 25 ] .
In regards to immunological outcomes, a concern associated with interruption of suppressive therapy is the potential for irreversible, viral-mediated CD4 T cell loss leading to disease progression [6,22].