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Example sentences for: subtree-neighbors

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Definition 3. Given a completely binary and rooted gene tree, the k -subtree-neighbors of a sequence q are defined as all sequences derived from the k -level parent node of q , except q itself (the level of q itself is 0, q 's parent is 1, and so forth).
We introduce this concept into our procedure as well, formalized as "subtree-neighbors" (illustrated in Figure 5):
Subtree-neighbors can be useful if there is (partial) agreement among their annotations (for example: if the subtree-neighbors of a query are NAD +-dependent isocitrate dehydrogenase and NADP +-dependent isocitrate dehydrogenase we can suppose that the query is likely to be a isocitrate dehydrogenase, but it is not possible to determine whether it is dependent on NAD +or NADP +).
A more reasonable annotation for this query would be to annotate it based on subtree-neighbors and hence call it a plant O-methyltransferase.
Furthermore, orthologs that are not also subtree-neighbors can be misleading (for a more detailed discussion of this, see below, and see Figures 10and 11for examples).