Words similar to subcomplex
Example sentences for: subcomplex
How can you use “subcomplex” in a sentence? Here are some example sentences to help you improve your vocabulary:
The lid subcomplex of the RP attaches to the base and is required for proteolysis of ubiquitin–protein conjugates, but not of unstructured polypeptides (Glickman et al.
Sarcospan is most tightly associated with the transmembrane sarcoglycan subcomplex, mutation of which causes autosomal recessive limb girdle muscular dystrophy (LGMD2C-2F) [ 7, 8, 9, 10, 11].
A second subcomplex, known as the dystroglycan complex [ 6], interacts directly with dystrophin in the cytoplasm and laminin in the extracellular matrix, thus providing a structural link between the inside and the outside of the cell.
COP10, which has been shown to interact with AtCOP1 in yeast two-hybrid experiment, encodes a ubiquitin conjugating enzyme (E2) variant [ 44 ] . The COP9 signalosome, an eight-subunit complex homologous to the lid subcomplex of the 26 S proteasome [ 45 ] , directly associates with SCF E3 complex and promotes deneddylation of the cullin subunit of SCF in both plant and animal cells [ 46 47 48 49 ] . The exact relationship between COP1 and the COP9 signalosome remains obscure; it is known, however, that in Arabidopsis the COP9 signalosome is required for COP1 to accumulate in the nucleus in the dark [ 29 ] . Although COP1 most likely plays a role in regulating protein degradation, attempts in reconstituting ubiquitination of HY5 by AtCOP1 have been unsuccessful.
A third subcomplex involves the dystrobrevins [ 7, 8] and syntrophins [ 9] which form a complex at the C-terminal region of dystrophin [ 10, 11, 12] and have an as yet unidentified function.
Loading...