Words similar to subcomplex
Example sentences for: subcomplex
How can you use “subcomplex” in a sentence? Here are some example sentences to help you improve your vocabulary:
In fact, Hurt and coworkers have recently demonstrated the in vitro assembly of a Nup subcomplex from entirely recombinant proteins [ 20 ] . Given the structural and functional similarities between vertebrate and yeast NPCs and the insertion of both into a pre-existing NEs, it is likely that NPC biogenesis occurs via a similar mechanism in all organisms.
A fraction of the total cellular Sec13p is isolated in a NPC subcomplex containing Nup84p, Nup85p, Nup120p, Nup145p-C, and Seh1p (a Sec13-related protein) [ 40 41 ] . Hurt and coworkers have also reported that ts sec13 mutants show enhanced growth defects when combined with a nup85Δ mutant, and result in the mislocalization of GFP-Nup49p to NE clusters and cytoplasmic foci [ 41 ] . This correlates with our observations of GFP-Nic96p and Nup170p-GFP in our sec13/npa2 mutant.
The Cdc53/Roc1 subcomplex stimulates the ubiquitination activity of Cdc34 [ 7 ] [ 8 ] . Upon association with the complex, Sic1 is extensively ubiquitinated and then degraded by the proteasome.
COP10, which has been shown to interact with AtCOP1 in yeast two-hybrid experiment, encodes a ubiquitin conjugating enzyme (E2) variant [ 44 ] . The COP9 signalosome, an eight-subunit complex homologous to the lid subcomplex of the 26 S proteasome [ 45 ] , directly associates with SCF E3 complex and promotes deneddylation of the cullin subunit of SCF in both plant and animal cells [ 46 47 48 49 ] . The exact relationship between COP1 and the COP9 signalosome remains obscure; it is known, however, that in Arabidopsis the COP9 signalosome is required for COP1 to accumulate in the nucleus in the dark [ 29 ] . Although COP1 most likely plays a role in regulating protein degradation, attempts in reconstituting ubiquitination of HY5 by AtCOP1 have been unsuccessful.
The lid subcomplex of the RP attaches to the base and is required for proteolysis of ubiquitin–protein conjugates, but not of unstructured polypeptides (Glickman et al.
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