Example sentences for: stimulus

How can you use “stimulus” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although heteroclitic peptide vaccination may drive T cells of mixed high and low RE, such a strong stimulus may be needed to induce an initial de novo T cell response.

  • We have characterized this requirement for repetition of the activity stimulus over days as a form of “cellular memory.”

  • The effect of the reduction of receptor number at the plasma membrane might be a rapid decrease of the physiological response to the stimulus.

  • This is supported by the finding that 48 hours of laminin stimulus is required for an increase in aggregate number, while in the 24-hour protocol reported at present only aggregate size is increased.

  • Although direct evidence that autoantigen cleavage fragments produced during cell death elicit autoantibody responses is still scarce, Pollard et al . reported that immunization of B10.S mice (H-2 s) with a 19 kDa proteolytic cleavage fragment of fibrillarin (derived from nonapoptotic cell death) elicited antibodies that are comparable with human anti-fibrillarin autoantibodies and those derived from mice exposed to mercury [ 40 ] . In a study using human sera, Greidinger et al . reported that the recognition of apoptosis-derived and oxidatively modified forms of the 70 kDa subunit of U1 small nuclear ribonucleoprotein autoantigen was associated with distinct disease manifestations [ 41 ] . Furthermore, Oriss et al . demonstrated that a combination of antigen-processing cells and a fragment of DNA topoisomerase I efficiently elicited autoreactive T-cell proliferation, whereas the full-length topoisomerase I required additional stimulus of exogenous interleukin-2 [ 42 ] .


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