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Example sentences for: stabilizing
How can you use “stabilizing” in a sentence? Here are some example sentences to help you improve your vocabulary:
We assume that the effects on sleep we observed in cry1 , 2 -/-mice are a result of a lack of cryptochrome -dependent inhibition of the transcriptional activation provided by the bHLH-PAS heterodimers CLOCK:BMAL1 and NPAS2:BMAL1 [ 19 20 37 ] , although cryptochromes also play a role in stabilizing and nuclear sequestration of PER proteins [ 38 ] , and in photoreception [ 39 ] . Lack of cryptochromes results in increased mRNA levels of CLOCK/NPAS2:BMAL1 target genes, including the circadian genes per1 and per2 [ 20 23 ] . The expression of these two genes is viewed as a state variable of the molecular circadian clock or a marker of CLOCK/NPAS2:BMAL1-induced transcription, although at least per1 transcription can also be (rapidly) induced by light [ 40 41 ] , through a CREB-dependent signaling pathway [ 42 43 44 ] . The observation of high brain levels of per1,2 transcripts under baseline conditions in cry1,2 -/-mice raises the possibility that these or other CLOCK/NPAS2:BMAL1 target genes are involved in the homeostatic regulation of sleep.
Early recognition of the contrast between the stabilizing influences of density-dependent population regulation, and potentially de-stabilizing influences of environmental variation [ 1 ] , laid a foundation for theoretical modeling of population stability in stochastic environments [ 2 ] that assumes renewed relevance in light of current developments in ecology and climate research [ 3 ] . Recently, for instance, numerous studies have documented the influences of global-scale climatic variation on the population dynamics of vertebrates in widely diverse ecosystems (see, e.g., [ 4 5 ] for reviews), including species interactions at the community level [ 6 7 8 ] . To our knowledge, however, no study has yet documented a simultaneous and direct influence of large-scale climate on the dynamics at all trophic levels in a single system.
stabilizing and improving the responsiveness of our network.
To recapitulate, Val29 and Lys61 make important stabilizing interactions with both A-4 and A-10.
Convention can scarcely be said to have had a stabilizing effect in the realms of education and psychology: both are so jargon-ridden that normal conversation with and even among practitioners is often impossible without the continual explanation of terminology and perpetual hedging of definition.
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