Example sentences for: stabilization

How can you use “stabilization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • TGFβ has been shown also to stabilize the mRNA of the smad7 gene [ 25 ] , while stabilization of RNA does not play a major role in regulation of the pthrp gene in MDA-MB-231 cells [ 19 ] . In addition, SB-203580 also inhibits p38 activity which has been shown to play a role in TGFβ signalling [ 36 37 38 39 40 41 ] . Hence, several factors could be responsible for the differential sensitivity of TGFβ-responsive genes to SB-203580.

  • This suggests a novel stabilization of cyclin D 1 protein in podocytes by HIV-1.

  • 0 μg/mlMG-132 may be related to the sustained elevation of MPF activity noted in rat oocytes exposed to MG-132 [ 42 ] and the stabilization of polyubiquitinated proteins and enhanced deubiquitination of nucleosomal histones in chromatin following proteasomal inhibition [ 62 ] .

  • A recent study in Drosophila suggested that Hh stimulates the pathway via Ptc degradation and, as a result, Smo is stabilized through extensive phosphorylation at the plasma membrane where it initiates signaling [ 5 ] . This led to speculation that a Ptc-regulated phosphatase may control the subcellular distribution and stability of Smo [ 5 ] . Although suggestive, the studies in Drosophila did not establish that phosphorylation, translocation or stabilization of Smo is required for pathway stimulation.

  • Instead, expression of Pop1p-ΔF in pop1 mutants led to even greater stabilization of Rum1p, potentially due to dominant negative interference with the residual activity of Pop2p and/or other F-box proteins.


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