Words similar to sp-a

Example sentences for: sp-a

How can you use “sp-a” in a sentence? Here are some example sentences to help you improve your vocabulary:

Insulin does not activate p44/42 MAPK and does not inhibit SP-A gene transcription via the MAPK pathway.
However wortmannin, at concentrations of 5-200 nM, abolished the insulin-mediated inhibition of SP-A mRNA levels at all concentrations tested (5-200 nM, Fig.
Wortmannin is a fungal metabolite that is a relatively selective inhibitor of PI 3-kinase with a half-maximal inhibition (IC 50 ) less than 5 nM [ 11 ] . In the wortmannin experiments, media were changed every 2 hours for a total of 12 hours in all of the conditions because wortmannin is unstable in solution at physiological pH [ 19 ] . The shorter incubation time with insulin in the wortmannin experiments resulted in a decreased inhibitory effect of insulin, i.e., an ~22% inhibition of SP-A mRNA levels (Fig.
In the control group, insulin significantly decreased SP-A mRNA levels to 57 ± 11% of control levels, however, in presence of 2 μM LY294002, insulin only decreased SP-A mRNA levels to 87 ± 15% of control levels versus 99 ± 3% of control levels in samples treated with LY294002 alone (mean ± SE, n = 4, n indicates the number of independent experiments).
Further studies will be required to elucidate the function of p70 S6 kinase in the nuclear events involved in SP-A gene transcription.