Example sentences for: sp-

How can you use “sp-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The 5' flank of exon 1b was searched with TransFac for potential transcription factor binding sites [ 34 ] . Potential binding sites for three transcription factors that have been shown to play key roles in muscle gene expression were found, Sp-1, Mef2 and SRF [ 36 ] . Four potential Sp1 and two Mef2 bindings sites were found within 300 bps of the transcription start.

  • These Sp-1 and Mef2 sites may play a role in muscle expression of the BDNF gene.

  • The absence of Sp-1 and Sp-3 from fully differentiated myocytes may explain the down-regulation in terminally differentiated muscle.

  • The proximal 5' flank of the FGFR1 gene has a similar clustering of SP-1, Mef2, and SRF sites [ 36 ] . The FGFR1 gene is expressed in terminally differentiated muscle, although at a lower level than in proliferating myoblasts [ 36 ] . The expression depends on Sp-1 sites in the proximal promoter and the binding of Sp-1 and Sp-3 to these sites.


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