Words similar to sox-

Example sentences for: sox-

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Several other HMG-box proteins also play important roles in lymphocyte development [ 17 ] . Mice doubly deficient in lymphocyte enhancement factor-1 (LEF-1) and T cell factor-1 (TCF-1) have a complete block in development of T cells [ 18 19 ] , while deficiency of SRY-box containing protein 4 (SOX-4) in mice results in a lack of pro-B cell expansion and mild perturbation of thymocyte development [ 20 ] . Unlike these HMG-box proteins, however, we find that the HMG-box of TOX is more closely related to the DNA binding domain of sequence-independent HMG-box proteins.
In Hoxc-8 transgenic chondrocytes, we found increased expression of Collagen II splice form A mRNA [ 24 ] . This is consistent with our earlier finding of at least 2-fold increased Collagen II mRNA expression by in situ hybridization and increased numbers of immature chondrocytes in Hoxc-8 transgenic mice [ 1 ] . Sox-5, which is normally expressed in proliferating chondrocytes [ 25 26 ] , is elevated in Hoxc-8 transgenic cells, again consistent with accumulation of immature chondrocytes.
Human SRY, murine SOX-4, SOX-17, and LEF-1 contain single HMG-box motifs and bind DNA in a sequence-specific fashion.
Sox-5 (NM 011444); forward primer: 5'-ATGGTGTGGGCGAAAGATGA-3'(1802-1821); reverse primer: 5'-GGCGGGCCTGCTCCT-3'(1946-1932).
1), LOC244579 mRNA (XM_146430), SOX-4 protein (NP_033264), SOX-17 protein (NP_035571), LEF-1 protein NP_034833), HMGB1 protein (CAA56631), upstream binding factor 1 (UBF-1) protein (NP_035681).