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Example sentences for: smi-

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[ 1 ] identified developmentally regulated nuclear antigens recognized by SMI-31 mAB in C6 rat glioma cells in vitro as well as glial and neuronal nuclei in vivo , suggesting the presence non-neurofilament epitopes.
As a previous study [ 13 ] had suggested nuclear staining by antibodies targeted to cytoplasmic proteins might be fixation dependent [ 4 ] or an artifact of fixation, we did a preliminary comparison of SMI-31 labeling of methanol vs. paraformaldehyde fixed cells.
[ 19 ] showed both SMI-31 and RT-97 strongly labeled nuclei of NB2a neuroblastoma cells.
Furthermore, nuclear labeling and DNA synthesis appeared tightly associated in SH-SY5Y cultures, consistent with the suspected role of lamins in DNA replication [ 8 ] . Others have reported SMI-31 labeling in glial as well as neuronal nuclei.
The nuclear localization of RT-97 and SMI-31 mAB could be the result of an association of phosphorylated NFs with nuclear components.