Words similar to smo

Example sentences for: smo

How can you use “smo” in a sentence? Here are some example sentences to help you improve your vocabulary:

Ptc shares sequence homology with molecules associated with vesicle trafficking and transporter activity, namely SCAP and NPC1 [ 36 40 41 42 ] ; if it also shares the activities of these molecules, as suggested by a recent study [ 36 ] , then the possibility of the existence of endogenous Smo ligands that are docked via Ptc should be explored.
These data show that the Hh-signaling inhibitors, but not structurally related inactive compounds, can significantly compete with the binding of the Hh agonist to Smo membranes.
Taken together, these data suggest that Hh protein and the agonist share the ability to stabilize Smo, but only Hh protein can destabilize Ptc.
Although no compelling data have been presented that directly link classic G-protein activation [ 37 ] to the canonical Hh pathway involving Ci/Gli stimulation [ 2 ] , recent studies show that under certain conditions Smo can engage G-protein subunits in a Ptc-dependent manner [ 38 ] and that G-protein-mediated cAMP modulation may underlie certain effects of Hh on neuronal tissue [ 39 ] .
We next compared binding of KAAD-cyclopamine, Cur61414 and Hh-Ag 1.5 to a constitutively active mutant of Smo (Smo act) or to wild-type Smo (Smo wt).