Words similar to smo

Example sentences for: smo

How can you use “smo” in a sentence? Here are some example sentences to help you improve your vocabulary:

This result demonstrates that a Hh-agonist derivative can be covalently crosslinked to Smo in living cells.
Figure 6bshows a bar graph of the bound counts from these binding assays (murine Smo, column 1; GFP, column 2; βAR, column 3; murine Ptc1, column 4; and a no-membrane plate control, column 5).
Since the Hh receptor, Ptc, serves to inhibit signaling, a small-molecule pathway activator would need to be capable of one of the following: first, interfering with the inhibitory effect that Ptc exerts on Smo; second, activating Smo without affecting Ptc; or third, activating the pathway downstream of Smo.
Shh -/-and Smo -/-embryos at this stage (6-8 somites) started to show fused ventral lips of the cephalic folds, and a single continuous optic vesicle, indicating lack of a clearly defined midline (red arrow, Figure 3g, and data not shown).
This oncogenic mutation has been found in human basal cell carcinoma [ 3 ] and the correspondingly mutated protein is capable of ligand-independent activation of the Hh pathway in cell-culture assays [ 11 ] . A kinetic and saturation binding assay with Smo act-containing membranes showed that this mutant protein binds the Hh agonist with an affinity identical to that of Smo wt(data not shown).