Example sentences for: smrt

How can you use “smrt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Intriguingly, human SMRT contains a sequence insertion at the position of the hydrophobic pair in the N-CoR β-box, which apparently leads to deletion of both residues (N-CoR/RMLS>SMRT/RLqagvmaS) [ 52 ] . Perhaps SMRT contains a different NR interacting motif or the N-CoR NR box sequence may be more complex than we have initially reported here.

  • The PGC-1 related protein PERC also binds ERα preferentially, and potentiates ERα activity more strongly than that of ERβ [ 38 ] . We recently observed that ERα binds the C-terminal NR interacting regions of N-CoR and SMRT in the presence of SERMs but not estrogens [ 39 ] . In this study, we report that ERβ interactions with N-CoR and SMRT are promoted by agonists and inhibited by SERMs.

  • Finally, SMRT also binds ERβ in the presence of estrogens, but we have not explored the structural features that promote this interaction.

  • SMRT Silencing Mediator of Retinoid and Thyroid Responsive transcription.

  • Agonist Dependent ERβ Interactions with N-CoR and SMRT


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