Example sentences for: smyd
How can you use “smyd” in a sentence? Here are some example sentences to help you improve your vocabulary:
This domain organization is conserved in several proteins in public databases, including the recently described SMYD1 (aka BOP) family of proteins [ 31 ] . Three isoforms of SMYD1 have been reported thus far (referred to by their original names, m-BOP1, m-BOP2 and t-BOP) that are products of a single gene that result from either alternative splicing or promoter usage [ 31 32 33 ] . m-BOP is essential for cardiac differentiation and morphogenesis while t-BOP is expressed in cytotoxic T lymphoctes.
The SMYD1 proteins are transcriptional regulatory proteins with chromatin-remodeling activities important in cardiac tissue, muscle and T lymphocytes [ 31 32 33 ] . Therefore, the new protein identified in this report is likely to play as yet undefined roles in transcription and has been assigned the official name SMYD2 to designate its relatedness to SMYD1.
Studies are currently underway to examine the function(s) of SMYD2 in testis and heart.
The SET domain is a common feature of proteins with histone lysine methyl transferase (HKMT) activity and has been identified in hundreds of proteins in organisms ranging from bacteria and viruses to humans [ 38 ] . The SMYD2 SET domain is separated into two parts (i.e.
This protein, now named SMYD2, contains SET and MYND domains that are characteristic of proteins with chromatin remodeling capabilities.
Loading...