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Example sentences for: sn

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These data show that SN56 cells express exclusively PLD2 and thus experimental manipulations of the activity of this PLD isoform were subsequently employed to determine if this enzyme is capable of producing choline for ACh synthesis in cholinergic cells.
It is instructive that, of the 53 Connections Map transcripts with altered expression (Table 1), 4 genes of diverse pathways but overlapping function best discriminate control from SN50-treated explants: PCNA, GR, BMP1, BMP3b.
Thus, we next analyzed SN50-treated and control E15 + 2 SMG explants using 2-D Western Multiprotein Arrays to determine protein differences.
Moreover, treatment of the macrophages with SN50, a cell-permeable peptide that specifically prevents activation of NF-κB by inhibiting its nuclear translocation [34], nearly abolished endotoxin-induced activation of resistin expression (Figure 4D).
In the present study, we used a cholinergic cell line, SN56 [ 17 ] , which is derived from the fusion of septal neurons of postnatal day 21 mice with N18TG2 murine neuroblastoma cells, as a model for cholinergic neurons, in order to determine the possible role of PLD 1 and PLD2 in generating choline for ACh synthesis.