Example sentences for: smg

How can you use “smg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To further demonstrate that SN50 treatment inhibited NB-κB activation, we evaluated if TNF supplementation would induce NF-κB translocation and SMG morphogenesis.

  • Although many "Ras/Raf" growth factor pathway transcripts were upregulated (Table 1), as a group they were poor predictors of SMG phenotype (control v.

  • E15 SMG primordia were cultured for 2 days in the presence or absence of the cell-permeable peptide SN50, a potent inhibitor of NF-κB nuclear translocation [ 33 34 35 ] . SN50 is composed of a nuclear localization sequence (NLS) for NF-κB p50 linked to a cell-permeable carrier [ 33 34 35 ] . SN50 blocks the intracellular recognition mechanism for the NLS on NF-κB, thus inhibiting NF-κB's translocation through the nuclear pore.

  • Gene/protein differences between control and NF-κB-inhibited phenotypes are not linearly causal of SMG dysplasia.

  • To determine which key pathways were activated, Western blot analyses of phosphorylated or cleaved proteins in E15+2 CONT and SN50-treated explants were conducted as previously described [ 5 ] . For this set of experiments, we first determined the specificity for each of the following antibodies purchased from Cell Signaling Technology (Beverly, MA) using E15 and E17 SMG homogenates: anti-phosphorylated Erk1/2 [phospho-p44/42 MAP kinase (Thr202/Tyr204)] antibody, anti-phosphorylated c-Raf(Ser259) antibody, anti-cleaved Caspase 3 (D 175) antibody, and anti-cleaved PARP (D214) antibody.


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