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Example sentences for: sites

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While the ER isoforms have contrasting effects on AP-1 activity in the presence of estrogens, ERα truncations that lack the NTD and ERβ both enhance AP-1 activity in the presence of SERMs [ 30 31 ] . Mutational analysis of ERα action at AP-1 sites suggests these effects may be related to N-CoR binding [ 39 ] , and we have proposed that SERM action at AP-1 sites may therefore involve contacts with corepressors [ 31 51 ] . The fact that ERα and ERβ show completely different ligand preferences of interaction with N-CoR suggests that the target for SERM activation at AP-1 sites may not be N-CoR in both cases.
These primers flank the triple repeat CAG and the HpaII sites in the first exon of the AR gene (Fig.
To hunt down modernista monuments with even greater accuracy, consider the self-guided tour, Ruta del Modernisme; its map details 50 sites of Barcelona modernista.
We adopted a group-by-sequence approach to first identify genes that contained the word-pair templates and then to test for significant associations with expression levels of the identified genes [ 27 ] . Significant associations between conserved word-pair templates and specific gene-expression changes and the prevalence of known transcription factor binding sites suggest that conserved word-pair templates comprise sequences important for multifactorial regulation in yeast.
The predicted transmembrane segments and phosphorylation sites are indicated in Figure 3.