Words similar to shrsp

Example sentences for: shrsp

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The GH rat was selected for systolic hypertension that increased with successive generations and maintained through filial matings [ 45 ] . In view of this, the Gly583Cys missense mutation of Abcg5 might result from occurrence of a de novo mutation during breeding at the stage of developing inbred WKY strains and propagated into the SHR and SHRSP lines.
The SHR strain was derived by selective inbreeding from the Kyoto outbred Wistar colony, and both SHR and SHRSP, as well as WKY strains have been maintained over many generations through brother-sister matings http://rgd.mcw.edu/tools/strains [ 43 44 ] . Healthy WKA and GH rat strains were also generated from outbred Wistar rat strains, but these strains were isolated independently in Japan and New Zealand, respectively (and maintained at other sites as well).
Another formal possibility not excluded is that the Gly583Cys missense mutation may have no significance in the accumulation of phytosterols in WKY, SHR and SHRSP, and that the alteration in the 3' UTR or even the intronic changes reported above may be the causative 'mutations'.
Abcg8 may have resulted from acquisition of a foreign chromosomal fragment during the Wistar rat strain breeding and established as homozygous change in the WKY, SHR and SHRSP, as well as GH rat strains.
WKY, SHR, SHRSP and GH rats are homozygous, Sprague Dawley and WKA strains wild-type and the Wistar sample heterozygous for this polymorphism (Fig.