Words similar to shr
Example sentences for: shr
How can you use “shr” in a sentence? Here are some example sentences to help you improve your vocabulary:
Evidence that sterolin-1 and sterolin-2 may heterodimerize has now been presented, based upon in vitro analyses [ 13 ] . However, our preliminary analyses of immunohistochemistry, using an antibody to sterolin-1 suggests that the pattern of expression in the liver and intestine is similar for both SD as well as WKY or SHR rats (Fig.
While this manuscript was in review, Scoggan et al also reported identifying Gly583Cys alteration in Abcg5 of SHR, SHRP and WKY rats [ 49 ] .
In this context, it is important to note that 3 other mutant loci have been reported in the SHR rat; missense mutations in the KAT-1 (kynurenine aminotransferase-1), Srebf-1 (sterol regulatory element binding factor-1) and CD36 (fatty acid translocase) are all present as homozygous changes [ 46 47 48 ] . The generation of congenic lines may assist with addressing many of these issues.
Recent linkage mapping studies mapped hypertension QTLs to a number of chromosomal regions in SHR and SHRSP rats [ 35 ] . Our FISH study assigned the STSL locus rat chromosome 6q12, a region where a cluster of blood pressure QTL with Lod score 4~6 has been reported to be present (M6MIT12-M6MIT3, 39 cM distance) in a New Zealand genetically hypertensive rat (GH rat) [ 35 ] . With respect to hypertension, although the SHR and SHRSP strains carry the Gly583Cys mutation, in extensive QTL mapping studies using these strains, no loci mapping to the rat STSL region have been reported [ 35 ] . In our study, the GH rat is neither sitosterolemic, nor has any nucleotide alteration at the STSL locus that would implicate this region as mutated.
It gave rise to the SHR and SHRSP strains.
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