Words similar to shrs
Example sentences for: shrs
How can you use “shrs” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results can help to elucidate the mechanism by which SHRs in general, and AR in particular, regulate gene expression.
These results can add more light to the mechanism by which SHRs, and AR in particular, regulate gene expression.
Coactivators are probably present in the nucleus in preassembled multicomplex units ready to associate to activated SHRs.
Upon ligand binding, the SHR undergoes conformational changes that involve releas e from the repressor proteins, and translocation to the nucleus where it can bind to specific hormone responsive sequences in the DNA of genes regulated by steroid hormones [ 1 2 ] . The mechanism by which SHRs affect the rate of RNA polymerase II-directed transcription likely involves the interaction of receptors with components of the transcription preinitialization complex.
Taken together, Stat3 enhances four different SHRs transcriptional activity in the presence of their corresponding ligand, suggesting that active Stat3 acts as a coactivator for nuclear receptors.
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