Example sentences for: shrs

How can you use “shrs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Coactivators are probably present in the nucleus in preassembled multicomplex units ready to associate to activated SHRs.

  • For GR and PR, we used the same reporter plasmid as for AR, ARE-TATA-luciferase, since it shows promiscuous response to all three SHRs [ 30 ] . For ER, we used ERE-TATA-luciferase reporter that is specific for estrogen.

  • The recent findings that members of the several different families of coactivators possess intrinsic histone acetyltransferase activity suggests that activated SHRs, and nuclear receptors in general, may also recruit these cofactors to remodel chromatin structure for better accessibility of the transcriptional machinery to DNA [ 5 6 ] .

  • Taken together, Stat3 enhances four different SHRs transcriptional activity in the presence of their corresponding ligand, suggesting that active Stat3 acts as a coactivator for nuclear receptors.

  • Effect of STAT3 on transcriptional activity of other SHRs


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