Words similar to sgcs

Example sentences for: sgcs

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However, studies on the SGCs suggest no evidence for a second covalent heme-binding site, implying that this histidine could have some other function.
Thus, the HNOB and HNOBA domains resemble functionally similar CACHE and CHASE domains, which have also been acquired by certain eukaryotic lineages via lateral transfer from bacteria [ 14 36 37 ] . A phylogenetic analysis of the guanylyl cyclase domains of the animal SGCs shows that their closest relatives are cyclases from various bacteria such cyanobacteria, and Leptospira (data not shown).
The length and conservation pattern of the N-terminal domain suggested that the N-terminal extension of the SGCs is likely to comprise of two globular domains in the least.
Though both the α and β subunits of SGCs are homologous throughout their entire length, only the β subunit contains the critical heme-binding residue.
Using sensitive sequence profile analysis we show that the heme-binding domain of the animal SGCs defines a novel family of ligand binding domains that are also widely distributed in bacteria.