Words similar to sgcs

Example sentences for: sgcs

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One of these, the HNOB domain, contains the heme-binding site of the SGCs and defines a family of small-molecule binding domains exclusively occurring in animals and bacteria.
Thus, the HNOB and HNOBA domains resemble functionally similar CACHE and CHASE domains, which have also been acquired by certain eukaryotic lineages via lateral transfer from bacteria [ 14 36 37 ] . A phylogenetic analysis of the guanylyl cyclase domains of the animal SGCs shows that their closest relatives are cyclases from various bacteria such cyanobacteria, and Leptospira (data not shown).
At convergence, this search detected, in addition to the soluble guanylyl cyclases from the animals, several bacterial proteins, including certain methyl-accepting chemotaxis receptors from bacteria such as Desulfovibrio and Clostridium . Transitive searches initiated with the small bacterial proteins that entirely correspond to the N-terminal-most domain of the SGCs also recovered the same set of proteins as observed in the earlier search, with e <.01.
These observations suggest that the N-terminal-most domain of the SGCs is evolutionarily mobile: it occurs in several distinct contexts with other domains in the same polypeptide, or in a stand-alone form.
The length and conservation pattern of the N-terminal domain suggested that the N-terminal extension of the SGCs is likely to comprise of two globular domains in the least.