Words similar to sgcs

Example sentences for: sgcs

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Though both the α and β subunits of SGCs are homologous throughout their entire length, only the β subunit contains the critical heme-binding residue.
One of these, the HNOB domain, contains the heme-binding site of the SGCs and defines a family of small-molecule binding domains exclusively occurring in animals and bacteria.
The length and conservation pattern of the N-terminal domain suggested that the N-terminal extension of the SGCs is likely to comprise of two globular domains in the least.
In such a scenario it could participate in allosteric regulation of the SGCs, similar to the GAF domains of the cyclic nucleotide phosphodiesterases [ 6 13 ] .
2 is present at much higher concentrations within the cell [ 22 23 ] . This ligand specificity of the NO binding domain of animal SGCs is very similar to bacterial cytochrome c' that likewise binds only NO and CO [ 24 ] . The N-terminal region of the α subunit has been shown to bind certain synthetic pyrazolopyridine ligands, which act as potents NO-independent agonists of cyclase activity [ 25 26 ] .