Words similar to sgcs
Example sentences for: sgcs
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The length and conservation pattern of the N-terminal domain suggested that the N-terminal extension of the SGCs is likely to comprise of two globular domains in the least.
The region of similarity shared by these bacterial proteins and animal SGCs encompassed more-or-less the entire middle region, which is present between the two other globular domains.
2 is present at much higher concentrations within the cell [ 22 23 ] . This ligand specificity of the NO binding domain of animal SGCs is very similar to bacterial cytochrome c' that likewise binds only NO and CO [ 24 ] . The N-terminal region of the α subunit has been shown to bind certain synthetic pyrazolopyridine ligands, which act as potents NO-independent agonists of cyclase activity [ 25 26 ] .
The SGCs also contain a second globular domain situated in between the heme-binding and cyclase domains.
One of these, the HNOB domain, contains the heme-binding site of the SGCs and defines a family of small-molecule binding domains exclusively occurring in animals and bacteria.