Words similar to sgc

Example sentences for: sgc

How can you use “sgc” in a sentence? Here are some example sentences to help you improve your vocabulary:

PSI-BLAST searches initiated with the C-terminal part of the SGC-specific extension (the region in between the above-detected N-terminal-most domain, and the C-terminal cyclase domain; human SGC1β, region: 200-370) recovered homologous regions from all other animal soluble guanylyl cyclases, and, additionally, N-terminal regions of histidine kinases from Nostoc and Anabaena species (eg.
Though SGC α-subunits lack the histidine, the region encompassing the HNOB domain in human SGC1α has been shown to be important for functional heme binding by the dimeric enzyme [ 28 ] . Hence, in addition to covalent heme binding, HNOB domains may also interact with it non-covalently.
A PSI-BLAST search was initiated with the conserved N-terminal extension of the SGC (human SGC1β, gi: 4504215, region 1-360), using an inclusion threshold of .01, and compositional bias based statistics to eliminate false positives arising due to peculiarities of sequence composition.
Studies on the human SGC1 suggest that the synthetic pyrazolopyridine ligand binds at site distinct from NO and heme, but requires the heme-binding site for its action [ 25 26 ] . This could imply a synergy or cooperation between these domains in heme interation and cyclase activation.
This region of similarity encompasses the entire length of these bacterial proteins, and includes the heme-liganding histidine of the SGC β subunits, and is likely to define a distinct globular domain.