Words similar to sgc

Example sentences for: sgc

How can you use “sgc” in a sentence? Here are some example sentences to help you improve your vocabulary:

PSI-BLAST searches initiated with the C-terminal part of the SGC-specific extension (the region in between the above-detected N-terminal-most domain, and the C-terminal cyclase domain; human SGC1β, region: 200-370) recovered homologous regions from all other animal soluble guanylyl cyclases, and, additionally, N-terminal regions of histidine kinases from Nostoc and Anabaena species (eg.
In order to probe this domain further we isolated this region from SGC1β (1-185) and seeded a PSI-BLAST search that was run to convergence.
This region of similarity encompasses the entire length of these bacterial proteins, and includes the heme-liganding histidine of the SGC β subunits, and is likely to define a distinct globular domain.
Studies on the human SGC1 suggest that the synthetic pyrazolopyridine ligand binds at site distinct from NO and heme, but requires the heme-binding site for its action [ 25 26 ] . This could imply a synergy or cooperation between these domains in heme interation and cyclase activation.
Though SGC α-subunits lack the histidine, the region encompassing the HNOB domain in human SGC1α has been shown to be important for functional heme binding by the dimeric enzyme [ 28 ] . Hence, in addition to covalent heme binding, HNOB domains may also interact with it non-covalently.