Words similar to sgc
Example sentences for: sgc
How can you use “sgc” in a sentence? Here are some example sentences to help you improve your vocabulary:
This region of similarity encompasses the entire length of these bacterial proteins, and includes the heme-liganding histidine of the SGC β subunits, and is likely to define a distinct globular domain.
As this long homologous N-terminal extension of SGC subunits does not map to any previously characterized domains, we sought to investigate its provenance through sequence analysis methods.
A PSI-BLAST search was initiated with the conserved N-terminal extension of the SGC (human SGC1β, gi: 4504215, region 1-360), using an inclusion threshold of .01, and compositional bias based statistics to eliminate false positives arising due to peculiarities of sequence composition.
Though SGC α-subunits lack the histidine, the region encompassing the HNOB domain in human SGC1α has been shown to be important for functional heme binding by the dimeric enzyme [ 28 ] . Hence, in addition to covalent heme binding, HNOB domains may also interact with it non-covalently.
PSI-BLAST searches initiated with the C-terminal part of the SGC-specific extension (the region in between the above-detected N-terminal-most domain, and the C-terminal cyclase domain; human SGC1β, region: 200-370) recovered homologous regions from all other animal soluble guanylyl cyclases, and, additionally, N-terminal regions of histidine kinases from Nostoc and Anabaena species (eg.