Words similar to rpn

Example sentences for: rpn

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BrdU labeling reagent (Amersham RPN202) in PBS was injected into pregnant females at 0.01 ml/gr body weight.
Notably, Rpn11 shares close homology with Csn5, which is also responsible for proteolytic activities in its respective complex.
While Csn5 is thought to impede the action of ubiquitin ligases through shaving cullins from their Rub1/Nedd8 modification (and possibly also by deubiquitinating substrates bound to the cullins), the outcome of Rpn11 inhibition will depend largely on whether Rpn11 participates primarily in shaving substrates from their chains, promoting release and rescue, or in trimming the polyubiquitin tag, allowing for proteolysis quality control (Figure 2).
This metalloprotease-like activity maps to the putative catalytic MPN+/JAMM motif of the lid subunit Rpn11 and lies at the heart of proteasome mechanism by linking deubiquitination with protein degradation.
Detection antibodies (all from Dako; 1:5,000 for 1 h at room temperature) were mouse-anti-goat Ig, mouse-anti-rat Ig, rabbit-anti-mouse Ig, and porcine-anti-rabbit Ig-HRP [ 66 ] . To visualize all transferred proteins, we used the ECL protein biotinylation labeling modules (RPN 2202, Amersham) and streptavidin alkaline phosphatase (V020402, Amersham) in accordance with the manufacturer's instructions.