Example sentences for: ribozyme-mediated

How can you use “ribozyme-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • MTT analysis and viable cell counts showed that ribozyme-mediated down-regulation of M6P/IGF2R also resulted in increased cell proliferation.

  • Most importantly, however, the lethal nature of an M6P/IGF2R-null phenotype is reversed in an IGF-II-null background [ 34 ] . Although we did not measure extracellular levels of IGF-II, our results show that ribozyme-mediated down-regulation of M6P/IGF2R leads to a decrease in IGF-II internalization, supporting the above possibility.

  • Our findings that ribozyme-mediated decrease in expression and functional activity of the M6P/IGF2R result in a growth advantage for MCF-7 cells indicate that this receptor acts as a negative regulator of cell growth.


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