Words similar to regulates
Example sentences for: regulates
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5 wild-type mice along with littermates mutant for the crx gene (which encodes a Paired type homeodomain transcription factor that directly regulates transcription of many photoreceptor-enriched genes); adult mouse retina; and microdissected outer nuclear layer, which consists entirely of rod and cone photoreceptors [ 11 ] . We examined this very large dataset for expression of genes known to be photoreceptor specific (Figure 2).
The dephosphorylation of phosphoproteins is universally catalyzed by protein phosphatases that are classified into two major functional groups, protein tyrosine phosphatase (PTP) and protein serine/threonine phosphatase (PP) although enzymes with various degrees of dual-specificity are also encountered [ 1 2 3 4 5 ] . The majority of Ser/Thr phosphatases belong to three classical groups, namely PP1, PP2A, and PP2B (calcineurin), and possess similar primary structures in their catalytic cores [ 2 3 6 ] . PP1, in particular, exhibits an extremely high degree of sequence conservation through evolution, and its orthologs and isoforms are found in all eukaryotic cells [ 6 7 ] . In various organisms, PP1 regulates such diverse cellular processes as cell cycle progression, protein synthesis, carbohydrate metabolism, transcription, and neuronal signaling [ 3 7 ] , underscoring its profound importance in biology.
None of Iowa's 99 counties regulates upkeep on rental property in unincorporated areas, according to county auditors.
An amino terminal, calcium-dependent lipid binding (CaLB or C2) domain regulates Ca 2+-mediated cPLA 2 translocation to intracellular membranes [ 9 ] . In vitro, membrane docking via the C2 domain is necessary and sufficient for catalysis and release of AA [ 10 ] . Binding of calcium ions by the cPLA 2 C2 domain is essential for the lipid association in vitro [ 11 12 ] and translocation in vivo [ 13 14 ] . In response to an increase in [Ca 2+] i , cPLA 2 translocates to the Golgi and ER, however translocation to Golgi occurs at a lower [Ca 2+] i [ 15 ] .
It was not known, however, whether P-TEFb regulates transcriptional elongation of all cellular genes or whether other factors promote transcriptional elongation on subsets of cellular genes.
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