Example sentences for: regulate

How can you use “regulate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The viability of collective bargaining as a means, once again, to regulate sweatshop conditions largely depends on the ability of UNITE!

  • Since, there is significantly less serum/cell in 2.5% serum samples, we conclude that factors in serum, at concentrations that maintain exponential growth, do not regulate Tag levels in these cell lines.

  • When avian Ocl were exposed to estradiol in vitro, the Ocl plasma membrane became depolarized and there was a marked decrease in potential, suggesting that estrogen may regulate osteoclasts through ion channel activities [ 27].

  • The Administrator shall have the authority to regulate the emission of hazardous air pollutants listed under section 112(b), other than mercury compounds, by electric utility steam generating units in accordance with the regime set forth in section 112(f)(2) through (4).

  • It is known that during clonal selection in the thymus, immature CD4, CD8 double positive cells develop into single positive CD4 or CD8 cells according to the relative affinity of their TCR to class II or class I molecules respectively [ 5 6 ] . These immature T-cells are selected in the thymic epithelium on the basis of their TCR interaction with either class I or class II MHC molecules [ 7 8 ] , thus generating two mutually exclusive subpopulations that are characterized by the expression of either CD4 or CD8 glycoproteins [ 9 ] . Earlier studies in the murine system have demonstrated that PMA and cAMP can modulate the expression CD4 and CD8 on developing thymocytes [ 10 11 12 13 ] . In keeping with these findings, ex vivo experiments with human thymocytes previously reported by our group, revealed that while phorbol esters can coordinately regulate the transcription of α and β TCR during intrathymic T cell differentiation [ 14 ] , cAMP selectively affected the transcription of the α and δ-TCR [ 15 16 ] . Together the murine data and our own findings support the hypothesis that in humans, TCR expression and CD4, CD8 commitment and selection may be regulated by the same signal-transduction pathways.


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