Example sentences for: regulate

How can you use “regulate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This developmentally important pathway contains several proteins, including APC, Frizzled, Axin and GSK3, which act in concert to promote the proteosomal degradation of β-catenin [ 13 14 ] . When APC is rendered inactive by mutation, β-catenin levels rise and the protein moves into the nucleus where it acts with Tcf/Lef cofactors to regulate transcription of c-myc , cyclin D and other oncogenes [ 15 ] .

  • In the past, peptides have sometimes been used to obtain information about protein:protein interactions as well as regulate their activity [ 2 3 ] . This has most often been accomplished with libraries consisting of peptides between <15 amino acids in length.

  • Instead of independently binding to specific DNA sequence to regulate transcription, Smads are now considered to be transcriptional modulators since their ability to regulate transcription is dependent, in most cases, on their physical interaction with other nearby DNA-binding transcription factors [ 11 ] . Thus, one of the fundamental questions in understanding Smad-regulated transcription is how Smads function as transcription modulators.

  • "Regulate them, control them, but legalize them," declared Johnson, and I can only ask, "What kept you?"

  • mth encodes a protein related to G-protein coupled receptors, and appears to negatively regulate life span, stress resistance and body size [ 14].


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