Words similar to reactivation
Example sentences for: reactivation
How can you use “reactivation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Of the six cell lines with RARB gene methylated, three (HT-3, MS751, and ME-180) exhibited reactivation upon treatment with 5-Aza-2' deoxycytidine or n-butyrate alone or the combination of the two.
Although it would be very difficult to prove that a CMV infection is the cause of EBV reactivation in clinical situations due to the gamut of factors that are involved, the fact that EBV reactivation was observed after in vitro CMV superinfections supports this role.
The BZLF1 gene of EBV is an immediate early gene involved in the first step of EBV reactivation, and its activity is controlled at the transcriptional level [ 60 61 62 63 64 65 66 ] , by protein-protein interactions [ 64 65 66 67 68 ] , and phosphorylation [ 64 69 70 ] . Perhaps CMV may cause the activation of certain cellular kinases, which in turn may activate BZLF1 transcript expression.
Therefore this study examined an in vitro CMV superinfection of EBV latently infected cell lines (BJAB-B1 and P3HR-1 cells) and the effect on EBV reactivation.
Frequent infection with herpesviruses has long been recognized in patients undergoing allogeneic transplantation [ 7 8 ] and in patients with acute leukemia [ 1 2 ] . In patients with acute leukemia it has been reported that as many as two thirds of seropositive patients can develop reactivation of herpes simplex virus infection during remission induction therapy [ 26 ] . The risk of CMV infection in acute leukemia patients was recognized almost 30 years ago [ 27 ] but is of particular concern in patients undergoing allogeneic transplantation [ 2 28 ] . EBV infection is frequently associated with post-transplantation lymphoproliferative disorders in T cell-depleted grafts [ 29 ] . As recently reported, HHV-6 can also be associated with bone marrow supression [ 30 ] , encephalitis and pneumonitis [ 7 8 ] after allogeneic transplantation.
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