Words similar to reactivation
Example sentences for: reactivation
How can you use “reactivation” in a sentence? Here are some example sentences to help you improve your vocabulary:
These B-cell lines were observed to be susceptible to a CMV superinfection and EBV reactivation occurs only in the cell lines superinfected with CMV.
Resistance to acyclovir (ACV) or penciclovir (PCV) generally arises by a single base mutation in either the HSV thymidine kinase (TK) or DNA polymerase (Pol) gene [for a review, see reference [ 5 ] ]. Unlike Pol, TK is not essential for virus replication in cell culture [ 7 ] , although in vivo analyses implicate it in HSV virulence, pathogenicity and reactivation from latency [ 4 8 16 22 ] . Since ACV and PCV are dependent upon HSV TK for monophosphorylation, an event obligatory for the formation of the active triphosphate inhibitor [ 14 ] , ACV risolates often exhibit high levels of cross-resistance to PCV [ 2 3 ] .
There are numerous studies observing CMV and EBV reactivation in immunosuppressed patients.
However, in vitro , it was most interesting to observe EBV reactivation only in the cell lines that were superinfected with CMV.
The MGMT gene exhibited promoter hypermethylation in four of the cell lines, which upon treatment with 5-Aza-2' deoxycytidine showed reactivation of expression in three (2102E-R, 833K-E, and Tera-2).
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