Words similar to rdrps

Example sentences for: rdrps

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Interestingly, the PSI-BLAST searches started with the sequences of the RDRP module of the RDRPs and the YRH proteins consistently retrieved the β' subunits of DDRPs, albeit at statistically not significant E-values.
These searches, e.g. the search initiated with the core RDRP module from Petunia (residues 37-775), readily retrieved RDRPs from plants, C. elegans , Dictyostelium discoideum , several fungi, and Giardia lamblia with statistically highly significant expectation (E) values.
The eukaryotic RDRP is part of a large ensemble of functionally linked proteins, which include the Dicer helicase-nuclease, PIWI family proteins, the Hen-2/Corymbosa-like RNA methylase, AlkB-related RNA demethylases, and Lin28-like RNA-binding proteins [ 1 45 46 ] . Since no closely related homologs of any of these proteins are encoded in the genomes of the phages that encode YRH proteins, the latter are unlikely to function in a biological context similar to that of the eukaryotic RDRPs.
The region of sequence similarity between the RDRPs and the β' subunits of DDRPs, that was detected in the searches described above, almost precisely mapped to the DPBB-fold catalytic domain of DDRP.
Here, we investigate the evolutionary history of RDRPs and DDRPs in an attempt to unveil the origin of the RDRP.