Words similar to rdrp
Example sentences for: rdrp
How can you use “rdrp” in a sentence? Here are some example sentences to help you improve your vocabulary:
The RDRP is present in one or more copies in a wide range of eukaryotes, from early-branching parabasalids, such as Giardia , to multicellular forms, including fungi, plants and animals [ 57 58 ] . This broad representation in eukaryotes, including organisms that are considered primitive, suggests that RDRP might have been encoded in the genome of the common ancestor of all modern eukaryotes.
Interestingly, the PSI-BLAST searches started with the sequences of the RDRP module of the RDRPs and the YRH proteins consistently retrieved the β' subunits of DDRPs, albeit at statistically not significant E-values.
In fact, it appears likely that the ancestral protein RNA polymerase, at the time of the differentiation of the β-type and β'-type DPBB domains, functioned as an RDRP because DNA probably had not evolved by that stage [ 96 ] . The switch of the ancestral enzyme to the DDRP activity and the emergence of the evolutionary precursor of RDRP might be tentatively linked to one another and associated with the advent of DNA.
These include a doublet comprised of a small and a polar residues preceding each of strands 3 and 6, a small residue after strand 2 (proline in the DDRP β' subunit and RDRP), bulky and polar residues in strand 3, a small residue immediately downstream of strand 5, a bulky residue in the loop between strands 5 and 6, and two hydrophobic residues in strand 6 (Fig.
However, despite extensive comparisons using PSSM and careful visual examination, we failed to detect any residual sequence similarity between DDRP and RDRP, outside the core DPBB domain containing the metal-binding active site.
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