Words similar to rdrp

Example sentences for: rdrp

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While we provide evidence that the catalytic cores of the RDRPs, their bacteriophage homologs and the DDRPs evolved from a common ancestor, the provenance of the rest of the conserved RDRP module and, accordingly, the evolutionary scenario for RDRP remain less clear.
A comparison of the RDRP and DDRP sequences using the Gibbs sampling method identified two conserved blocks, which were highly statistically significant (E < 10 -16) within the analyzed sequence set.
This domain adopts the DPBB fold, in which the signature DbDGD motif, shared by RDRP and DDRP, is ensconced in the insert between the ultimate and penultimate β-strands.
In fact, it appears likely that the ancestral protein RNA polymerase, at the time of the differentiation of the β-type and β'-type DPBB domains, functioned as an RDRP because DNA probably had not evolved by that stage [ 96 ] . The switch of the ancestral enzyme to the DDRP activity and the emergence of the evolutionary precursor of RDRP might be tentatively linked to one another and associated with the advent of DNA.
Taken together, all these observations point to a scenario for the origin of the RDRP, under which the RDRPs and the YRHs diverged from the DDRPs at a stage of evolution that succeeded the divergence of the DPBB domains of the β and β' subunits (Fig.