Words similar to rdrp

Example sentences for: rdrp

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These include a doublet comprised of a small and a polar residues preceding each of strands 3 and 6, a small residue after strand 2 (proline in the DDRP β' subunit and RDRP), bulky and polar residues in strand 3, a small residue immediately downstream of strand 5, a bulky residue in the loop between strands 5 and 6, and two hydrophobic residues in strand 6 (Fig.
As components of the functional viral RdRP, N and P bind each other [ 23 ] . It was, therefore, important to ask whether they need each other (or other viral proteins) in order to interact with profilin, or whether they are individually capable of binding profilin.
Specifically, if the de novo synthesis of the essential subunits of viral RdRP - such as L or P - is inhibited, it will abolish the bulk of viral transcription and replication, and hence, viral translation [ 3 ] .
The functions of these previously unnoticed modules and the nature of the apparent congruence in the evolution of the two RDRP subunits in a subset of bacteria remain to be elucidated.
The minimal constituents of a nonsegmented negative-strand RNA viral RdRP are the viral large protein L and the phosphoprotein P [ 23 ] . While the L protein is believed to possess the basic RNA polymerase function, the P protein serves as its transcription factor.