Example sentences for: rdrp

How can you use “rdrp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Nevertheless, the extended similarity between the YRH and RDRP sequences and the presence of potential nucleic-acid-binding modules, such as a C-terminal Zn-ribbon in the SpβC2 YonO protein, suggest that the YRH proteins also have a RNA polymerase activity.

  • The minimal constituents of a nonsegmented negative-strand RNA viral RdRP are the viral large protein L and the phosphoprotein P [ 23 ] . While the L protein is believed to possess the basic RNA polymerase function, the P protein serves as its transcription factor.

  • For example, searches seeded with the RDRP (RrpB gene product) sequence from Dictyostelium (gi:14475571) and the pattern [GAS]-D- [FLYMQN]-D- [G]-D-X- [ACLIVMFY]-X- [ACLIVMFY] detected the rice DDRP catalytic subunit with an E-value of 0.048.

  • The RNA genome of RSV is about 15 kb long and contains 11 documented protein-coding genes [ 13 ] . Three viral proteins are minimally required to reconstitute the functional transcription complex of NNR viruses [ 3 ] : the nucleocapsid protein (N) that wraps the negative-strand genome RNA and its full-length complement, the positive-strand antigenome RNA, thus converting them into highly nuclease-resistant, chromatin-like templates; the large protein (L), which is the major subunit of the RdRP; and the phosphoprotein (P), which is the smaller subunit of RdRP and an essential transcription factor of L [ 19 20 21 22 ] . In RSV, optimal transcription, although not replication, additionally requires the transcription antitermination protein M2-1 [ 13 ] . In addition, cellular actin, and to a lesser extent, profilin, are also required for viral transcription [ 17 18 ] .

  • Additionally, a search of the NR database with a position-specific scoring matrix (PSSM) that included all unique RDRP and YRH sequences detected, with borderline E-values, a large protein from Corynebacterium glutamicum (Cgl1702), which also contained a DXDGD motif.


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