Example sentences for: proteosome

How can you use “proteosome” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Proteolysis of important regulatory proteins is a key aspect of cellular regulation in eukaryotes [ 60 61 ] and there is evidence that the ubiquitin-proteasome pathway is important in implementation of the plant defense response [ 62 63 64 ] . Proteosome subunit genes are induced in response to stresses [ 65 66 ] and several regulatory subunits were identified in the stress cDNA collection.

  • NF-κB activation is controlled by its inhibitory protein I-κBα which when phosphorylated on ser32 and ser36 marks it for degradation by the 26S proteosome complex.

  • SOD1 aggregates have been widely observed in mutant SOD1 transgenic mice and in human ALS caused by SOD1 mutations [ 11 14 35 36 ] . In cultured cells, mutant SOD1 forms high molecular weight aggregates when the cells are stressed by high mutant protein expression [ 51 ] , proteosome inhibition [ 52 ] and serum withdraw [ 27 ] . The role of mutant SOD1 aggregation, however, remains unclear.


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