Example sentences for: proteosomal

How can you use “proteosomal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This developmentally important pathway contains several proteins, including APC, Frizzled, Axin and GSK3, which act in concert to promote the proteosomal degradation of β-catenin [ 13 14 ] . When APC is rendered inactive by mutation, β-catenin levels rise and the protein moves into the nucleus where it acts with Tcf/Lef cofactors to regulate transcription of c-myc , cyclin D and other oncogenes [ 15 ] .

  • The mutant gene encodes β-catenin protein stabilized by alteration of a phosphorylation site required for proteosomal degradation.


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