Example sentences for: prfa

How can you use “prfa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The prfA gene codes for a transcriptional regulator, which controls the virulence genes hly, plcA, plcB, mpl and actA , as well as negatively regulating itself [ 31, 32].

  • The three measurements of log 2 (Caco-2 T 0 /reference) from the parallel set were averaged to define the pattern of expression in uninfected cells at the beginning of the synchronized parallel time course, and was then used to zero transform the mock, wild-type, actA and prfA parallel infections.

  • It is likely that differences in the transcriptional program would emerge at later stages of infection, as wild-type and actA bacteria replicate and kill the cells, and prfA do not.

  • It is not surprising that these bacteria are adherent, as InlA expression is only partly dependent on PrfA [ 46].

  • Three strains of L. monocytogenes were used; wild type (10403S), a mutant for the transcriptional regulation of virulence genes, prfA (DP-L1075) [ 33], and a mutant deficient for intracellular motility, actA (DP-L1942) [ 30].


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