Words similar to prfa

Example sentences for: prfa

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Mutant bacteria with a transposon insertion in prfA (DP-L1075) [ 33] adhere to the host-cell surface, and induce their own uptake into a phagocytic vacuole, presumably through low-level expression of the internalins, but cannot escape from the phagocytic vacuole into the cytoplasm.
Three strains of L. monocytogenes were used; wild type (10403S), a mutant for the transcriptional regulation of virulence genes, prfA (DP-L1075) [ 33], and a mutant deficient for intracellular motility, actA (DP-L1942) [ 30].
The prfA gene codes for a transcriptional regulator, which controls the virulence genes hly, plcA, plcB, mpl and actA , as well as negatively regulating itself [ 31, 32].
For the prfA analysis, wild-type and actA were a single class.
We repeated the experiments carrying out parallel 4-hour time courses simultaneously for mock infections, wild-type (10403S), Δ actA (DP-L1942) and Δ prfA (DP-L1075), with time points taken at 0, 60, 120 and 240 minutes after infection.