Example sentences for: prfa

How can you use “prfa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The prfA gene codes for a transcriptional regulator, which controls the virulence genes hly, plcA, plcB, mpl and actA , as well as negatively regulating itself [ 31, 32].

  • It is likely that differences in the transcriptional program would emerge at later stages of infection, as wild-type and actA bacteria replicate and kill the cells, and prfA do not.

  • By the same sets of criteria described above for studying the difference between wild-type and actA infections, we examined whether there were any genes reproducibly induced by cytoplasmic bacteria (wild-type or actA ) but not by the avirulent organism ( prfA ). In this dataset, no genes passed these criteria during the first 4 hours of infection.

  • To this end, we have examined the global transcriptional response of a human intestinal epithelial cell line, Caco-2, to infection by L. monocytogenes and isogenic mutants which are disrupted in the actA or prfA gene.

  • For the actA analysis, the wild-type and prfA were grouped as a single class.


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