Words similar to post-transcriptional
Example sentences for: post-transcriptional
How can you use “post-transcriptional” in a sentence? Here are some example sentences to help you improve your vocabulary:
Post-transcriptional gene silencing by such dsRNA molecules should facilitate the reverse genetics and functional genomics of RNA genomes.
We anticipate that other examples of sequence motifs that are conserved in orthologs of the three dipterans and that are strongly complementary to miRNAs will be prime candidates to test as new examples of miRNA-mediated post-transcriptional gene regulation.
Over the last decade, RNA interference (RNAi), mediated by short interfering double-stranded RNA molecules (siRNA or dsRNA), has been gradually recognized as a major mechanism of post-transcriptional gene silencing (PTGS) in species as diverse as plants, Drosophila, and C. elegans [ 1 ] . Recently, 21-nucleotide long dsRNA molecules corresponding to specific mRNA sequences, when introduced into mammalian cells in culture, have been shown to be highly effective in degrading the cognate mRNAs and thus abrogating the expression of the corresponding proteins [ 2 ] . Although the exact mechanism of PTGS is currently unknown and is an area of intense research, the successful use of this phenomenon in cultured mammalian cells has raised the exciting prospect that it can be used as a simple strategy for phenotypic ablation of mammalian gene function ex vivo without the time-consuming and expensive construction of transgenic animals.
Previous studies have shown that Gad1 can be regulated at the post-transcriptional and translational level.
Completion of the sequencing of mouse and other laboratory animal genomes will facilitate the production of more directed arrays, but until the full transcriptional and post-transcriptional (that is, alternative splicing) repertoire of every cell type in every condition in every strain at every age is mapped out, developing a fully representative array is unrealistic.
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