Words similar to post-transcriptional
Example sentences for: post-transcriptional
How can you use “post-transcriptional” in a sentence? Here are some example sentences to help you improve your vocabulary:
We hypothesized that association of mRNAs with the cytoskeleton may be a more widespread post-transcriptional regulatory mechanism that extends to a larger subset of transcripts than is currently recognized.
Completion of the sequencing of mouse and other laboratory animal genomes will facilitate the production of more directed arrays, but until the full transcriptional and post-transcriptional (that is, alternative splicing) repertoire of every cell type in every condition in every strain at every age is mapped out, developing a fully representative array is unrealistic.
Here, we identified bacteriophage homologs of the eukaryotic RDRP, which is involved in post-transcriptional gene silencing.
Over the last decade, RNA interference (RNAi), mediated by short interfering double-stranded RNA molecules (siRNA or dsRNA), has been gradually recognized as a major mechanism of post-transcriptional gene silencing (PTGS) in species as diverse as plants, Drosophila, and C. elegans [ 1 ] . Recently, 21-nucleotide long dsRNA molecules corresponding to specific mRNA sequences, when introduced into mammalian cells in culture, have been shown to be highly effective in degrading the cognate mRNAs and thus abrogating the expression of the corresponding proteins [ 2 ] . Although the exact mechanism of PTGS is currently unknown and is an area of intense research, the successful use of this phenomenon in cultured mammalian cells has raised the exciting prospect that it can be used as a simple strategy for phenotypic ablation of mammalian gene function ex vivo without the time-consuming and expensive construction of transgenic animals.
The above results show that the level of TAF II 135 and TBP is strictly controlled during the differentiation of F9 cells by a post-transcriptional mechanism involving targeted proteolysis.
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