Words similar to post-tetanic
Example sentences for: post-tetanic
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In hippocampal slice preparations, γ oscillations can be triggered by high frequency tetanic stimuli, called post-tetanic γ oscillations [ 10 11 12 13 ] . In addition to post-tetanic γ oscillations, the γ oscillations also can be elicited by metabotropic glutamate receptor agonists, carbacol, or free extracellular Mg 2+ [ 18 19 ] . In this study, we report that γ oscillations can occur in a model of a clinical disorder, namely hyperthermia.
For post-tetanic γ oscillations, the slow depolarizations were mediated by tetanic stimulation-induced GABAergic depolarizing action [ 20 21 22 23 ] . This GABAergic depolarization is attributed to the tetanic stimulation-induced accumulation of intracellular chloride [ 24 ] and extracellular potassium [ 22 ] . For hyperthermic γ oscillations, heating causes a Na +/K +pump failure [ 8 ] , in turn resulting in the accumulation of intracellular Na +and Cl -, as well as extracellular K +, finally causing a slow membrane depolarization.
In our previous report, the extracellular K +indeed elevated dramatically during hyperthermia-induced epileptiform-like population spikes and SDs [ 8 ] . Field effects further contribute to post-tetanic γ oscillations [ 25 26 ] . High Frequency tetanic stimuli leads to cellular swelling [ 27 28 ] , increasing extracellular resistance.
In the same slice, heating to 38°C ( 2Ab) evoked population oscillation very similar to those of post-tetanic γ oscillations.
Bath-application of 10 μM BMI for 20 min abolished post-tetanic γ oscillations.
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