Words similar to polymorphonuclear
Example sentences for: polymorphonuclear
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A substantial difference between gradient-separated PBMC and circulating cells in vivo is the lack of plasma, platelets and polymorphonuclear cells as a result of the apheresis process.
The polymorphonuclear leucocytes (PMN) were isolated from pooled normal healthy human blood by Ficoll Hypaque density gradient centrifugation.
However, density gradient separation of PBMC almost totally compensated for these shifts by eliminating polymorphonuclear cells, eosinophils and basophils (Figure 1c), and leaving a mononuclear cell population comparable with pre-IL-2 treatment samples.
The process of membrane vesiculation and MP-release in platelets has been shown to require a calpain-dependent dissociation of membrane proteins from the submembrane cytoskeleton and most likely involves intracellular signaling by platelet protein kinases [ 10 ] . Besides platelets stimulated by various agonists such as thrombin with collagen or the complement complex C5b-9 [ 7 11 ] , a release of PS-containing membrane MP was demonstrated in other cell types such as endotoxin-stimulated monocytes [ 12 ] , polymorphonuclear leucocytes stimulated with the chemotactic peptide FMLP [ 13 ] or apoptotic T-lymphocytes [ 14 ] . The normal restriction of PS to the inner surface of the plasma membrane becomes perturbed in apoptotic cells [ 15 16 ] . When exposed, PS is a determinant for phagocyte recognition of cells to be cleared.
With respect to adhesion, adhesion of polymorphonuclear leukocytes has been shown to be enhanced by treatment with NOS inhibitors, similarly Hokari et al.