Example sentences for: polymorphisms

How can you use “polymorphisms” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since the polymorphisms present in MOLD do not affect restriction sites, this experiment was done using SSCP to distinguish the alleles.

  • Mutations in the IL-6 promoter region may play a role in the tumorigenic effects of constitutive IL-6 expression in prostatic carcinoma cells [ 33 ] . Such polymorphisms have been described for the IL-6 receptor in Kaposi's sarcoma, and are believed to play a role in IL-6-mediated progression of this type of cancer [ 32 ] .

  • Although we have not determined the single-nucleotide polymorphism rate between the libraries, we observed four cases of insertional polymorphisms in which BACs contain transposable elements that are absent from the Release 2 WGS assembly; two on the X, a gtwin element in BACR33A08 and a 412 element in BACR29P19; one on chromosome 2, a roo in BACR01K07 and one on chromosome 3, a roo in BACR02C22.

  • A unique strength of ISGS is that the protocol was specifically developed to permit valid future pooled analyses with the ongoing affected sibling pair linkage study SWISS [ 24 53 ] , which uses genome-wide screening within a cohort of pedigrees to identify chromosomal regions - rather than specific polymorphisms - that are linked to stroke.

  • Sequencing studies of human transcriptomes and genomes have identified hundreds of thousands of single nucleotide polymorphisms (SNPs), the most common type of human genetic variation [ 1 ] . Human SNPs are being assembled into extremely high-density genetic maps that are anticipated to considerably expand the remit of genetic analyses [ 2 ] . Broad availability of SNPs for candidate genes will enhance pharmacogenomic and complex trait association studies.


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