Words similar to polymorphism
Example sentences for: polymorphism
How can you use “polymorphism” in a sentence? Here are some example sentences to help you improve your vocabulary:
Nonetheless, our observation shows that this polymorphism is an independent determinant for insulin sensitivity and is in agreement with the notion that a higher level of vitamin D is associated with increased insulin sensitivity [ 32].
[ 14 ] found that cerebrovascular disease was associated with both the C/B genotype of the VNTR polymorphism (OR, 2.83; 95% CI, 1.16 to 7.07; P = 0.0114) and the β allele of the HPA-2 polymorphism.
3 [ 43 ] . Methylphenidate, the primary stimulant used in pharmacological treatment of ADHD, was shown by PET imaging to block the dopamine transporter [ 44 ] . ADHD patients have also been found to show higher levels of DAT1 in the striatum [ 45 ] . The most well studied polymorphism is a VNTR in the 3' untranslated region of the DAT gene [ 46 ] . Since this VNTR is not in the coding region of the DAT gene, it does not affect the protein sequence of the dopamine transporter, but may affect the translational efficiency and thus the amount of protein expressed.
Furthermore, if important functional mutations should arise in noncoding regions without significant disequilibrium with the site of a screened polymorphism, the association analysis may exclude the true disease susceptibility locus.
Clearly there is substantial controversy surrounding this locus and the A54T polymorphism in the pathogenesis of insulin resistance and T2DM as described above.