Example sentences for: polyadenylation

How can you use “polyadenylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In studying the architecture of the 3'-transduced sequences, we found that only a fraction had a recognizable polyadenylation signal.

  • A unique fragment in the exon 10-11 region is followed by a correctly spliced exon 11B and a part of exon 12, which splices backwards from a unique donor site to a unique partial version of exon 9, and continues directly to a unique fragment of exon 20, terminating at the common late polyadenylation signal.

  • As the protocols used to extract and purify mRNAs from tissue lysate for the libraries cited in this study all relied on the presence of polyadenylation sites, we generally do not expect to find bacterial transcripts.

  • Many instances of internal alternative splicing as well as alternative polyadenylation will have been missed, as our dataset of cDNA sequences contained many more 5' ESTs than 3' ESTs or complete cDNAs.

  • This 3' sequence becomes transduced, along with the L1 sequence, to a new genomic locus; a hypothesized cause of the imprecision of the 3' end of the L1 transcript is the weak polyadenylation signal in the L1 element [ 28 ] . Clear indications of 3' transduction have been documented in cases where an L1 inserted into the dystrophin gene [ 29 ] , APC [ 30 ] and CYBB [ 31 ] . All these disease-producing L1 insertions, the boundaries of which were defined by flanking TSDs, contained novel sequences downstream of the L1 sequence itself.


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