Example sentences for: polyadenylation

How can you use “polyadenylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The first indication that mammalian proteins with Q/N-rich domains can form self-propagating prions came from recent work with a regulator of translation cytoplasmic polyadenylation element-binding protein (CPEB) from Aplysia neurons (Si et al.

  • The presence of multiple consensus polyadenylation signals both before and after the one utilized in this transcript is consistent with the latter hypothesis.

  • The vast majority of these are due to alternative splicing (an introduced bias; see Materials and methods), but 13% are due to alternative promoters and 6% to alternative polyadenylation sites.

  • Indeed, the TSDs for the 3'-transduction events that lack a polyadenylation signal are A-rich at their 5' ends (Table 1), indicating that the target site at which priming occurred would have been T-rich.

  • demonstrated this experimentally in cultured cells by cloning a reporter gene containing a splice acceptor downstream from the polyadenylation signal of an intact L1 element [ 28 ] . This engineered L1 retrotransposed into transcriptionally active genomic loci, allowing the co-mobilized reporter to be expressed after being spliced into a transcript expressed in these cells, effectively creating a chimeric mRNA [ 28 ] .


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