Words similar to polyadenylation
Example sentences for: polyadenylation
How can you use “polyadenylation” in a sentence? Here are some example sentences to help you improve your vocabulary:
..) [ 23 ] . Since these poly(A) tails themselves contain polyadenylation signals, it is possible that their assignments as poly(A) tails are false positives, and the real tail formed by polyadenylation has shortened over time and is not detectable [ 44 46 47 ] . Four of the remaining L1-TDs for which no polyadenylation signal was found appeared to result from multiple sequential transduction events; we did not have family members that align with the 3' end of the transduced sequence to determine whether the poly(A) stretch could have been encoded in DNA.
We manually inspected these sequences for the presence of either AATAAA or ATTAAA polyadenylation signals no more than 100 nucleotides upstream of the poly(A) tail that preceded the 3' TSD [ 43 ] . We were able to identify a polyadenylation signal in 11 of our 25 examples of 3' transduction events (Table 2and Figure 3a).
0 was generated as follows: First, 7T40 was digested with Eco RI, thus liberating the Hsp70 polyadenylation signal sequence.
One explanation for this sequence structure is that the transcripts were polyadenylated at the same location, and the polyadenylation signal mutated beyond recognition after the insertion event occurred; interestingly, Ovchinnikov et al . reported that polyadenylation signals tend to degrade rapidly after L1 insertion [ 44 ] . A second explanation is that the poly(A) sequence is encoded in DNA and either the transcript was degraded up to the position of the A-rich sequence or RNA polymerase II failed to elongate the message past the A-rich sequence; the resulting transcript would then resemble one that had been polyadenylated.
1) lacking the 37-nucleotide poly(A) tail and therefore ending with the first three nucleotides (AAT) of the putative polyadenylation signal.
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