Example sentences for: pmediates

How can you use “pmediates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • SCF Pop1p-Pop2pmediates polyubiquitylation of Rum1p in vitro

  • In addition, based on overexpression, distinct SCF Pop1pand SCF Pop2pcomplexes were proposed to target unknown substrates, but no biochemical evidence of their activity was provided [ 18 ] . To address these questions, we cloned two additional subunits of SCF Popand performed a detailed characterization of its activity in vitro and in vivo . Our results indicate that heterooligomeric SCF Pop1p-Pop2pmediates Rum1p ubiquitylation whereas distinct SCF Pop1pand SCF Pop2pcomplexes target unknown nuclear and cytoplasmic substrates, thereby generating combinatorial diversity of SCF function in fission yeast.

  • Taken together these results strongly suggest that SCF Pop1p-Pop2pmediates the polyubiquitylation of CDK phosphorylated Rum1p in vitro .


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