Words similar to pmediates
Example sentences for: pmediates
How can you use “pmediates” in a sentence? Here are some example sentences to help you improve your vocabulary:
SCF Pop1p-Pop2pmediates polyubiquitylation of Rum1p in vitro
In addition, based on overexpression, distinct SCF Pop1pand SCF Pop2pcomplexes were proposed to target unknown substrates, but no biochemical evidence of their activity was provided [ 18 ] . To address these questions, we cloned two additional subunits of SCF Popand performed a detailed characterization of its activity in vitro and in vivo . Our results indicate that heterooligomeric SCF Pop1p-Pop2pmediates Rum1p ubiquitylation whereas distinct SCF Pop1pand SCF Pop2pcomplexes target unknown nuclear and cytoplasmic substrates, thereby generating combinatorial diversity of SCF function in fission yeast.
Taken together these results strongly suggest that SCF Pop1p-Pop2pmediates the polyubiquitylation of CDK phosphorylated Rum1p in vitro .