Words similar to phyletic
Example sentences for: phyletic
How can you use “phyletic” in a sentence? Here are some example sentences to help you improve your vocabulary:
In addition to the variable phyletic patterns, the proteins of the P60-like family also show extensive lineage-specific diversification in terms of their domain architectures (Figure 3).
Based on phyletic distribution and contextual information, we conclude that these enzymes may play a critical role in the interface between nucleotide and polyphosphate metabolism.
Studies in Escherichia coli have shown that, although RecA is the principle protein involved in pairing and strand exchange, unrelated proteins, that have a much more restrictive phyletic distribution, can also promote similar reactions in a RecA dependent or RecA-independent manner [ 3 ] . These alternative or additional mediators of homologous recombination include the well-characterized prophage RecT, phage λ Redβ and phage P22 ERF proteins [ 4 5 ] . Similarly, in yeast and vertebrates, the RAD52 protein is involved in the pairing and strand exchange reaction and can promote recombination in a RAD51 (the eukaryotic RecA homolog)-dependent or independent manner [ 6 ] . The RecT protein works in conjunction with the RecE-nuclease [ 7 ] and was initially described in genetic studies on the complemention of mutations in the RecBCD pathway of DNA repair [ 8 9 10 ] . Biochemically, RecT has been shown to bind single-stranded (ss) DNA 3' overhang regions generated by the RecE nuclease, and promote strand exchange between homologous DNA partners by assisting the pairing of complementary single-stranded regions [ 4 10 ] . The reaction catalyzed by the RecT/RecE system is similar to that described for the phage λ exonuclease (exo/Redβ) and the single-strand annealing protein Redβ.
Here, we describe the results of an in-depth sequence analysis of these proteins and delineate their evolutionary relationships and phyletic horizon in available genomes.
An analysis of the phyletic patterns suggests that the p24 family had already differentiated into at least four distinct subfamilies in the common ancestor of plants, animals and fungi.
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