Words similar to phyletic
Example sentences for: phyletic
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There are 10 clearly identifiable orthologous lineages within this family which have varying phyletic distributions in bacteria (Figure 3).
Studies in Escherichia coli have shown that, although RecA is the principle protein involved in pairing and strand exchange, unrelated proteins, that have a much more restrictive phyletic distribution, can also promote similar reactions in a RecA dependent or RecA-independent manner [ 3 ] . These alternative or additional mediators of homologous recombination include the well-characterized prophage RecT, phage λ Redβ and phage P22 ERF proteins [ 4 5 ] . Similarly, in yeast and vertebrates, the RAD52 protein is involved in the pairing and strand exchange reaction and can promote recombination in a RAD51 (the eukaryotic RecA homolog)-dependent or independent manner [ 6 ] . The RecT protein works in conjunction with the RecE-nuclease [ 7 ] and was initially described in genetic studies on the complemention of mutations in the RecBCD pathway of DNA repair [ 8 9 10 ] . Biochemically, RecT has been shown to bind single-stranded (ss) DNA 3' overhang regions generated by the RecE nuclease, and promote strand exchange between homologous DNA partners by assisting the pairing of complementary single-stranded regions [ 4 10 ] . The reaction catalyzed by the RecT/RecE system is similar to that described for the phage λ exonuclease (exo/Redβ) and the single-strand annealing protein Redβ.
Figure 1shows a genome-COG matrix that reveals the phyletic (phylogenetic) patterns of the presence or absence of the orthologs across the spectrum of the sequenced genomes [ 18] for each of the 52 pairs of fusion-linked COGs containing cross-kingdom fusions.
This protein is not homologous to the canonical TS, but its orthologs in bacteria and archaea show an almost perfect complementary phyletic distribution (COG1351).
The RAD52 superfamily shows a sporadic phyletic distribution, and even in the crown-group eukaryotes, might have been secondarily lost in certain lineages, such as plants, nematodes and insects.
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