Example sentences for: phagocytic

How can you use “phagocytic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mycobacteria enter macrophages primarily by conventional receptor-mediated phagocytic pathways [ 3 ] . Following phagocytosis, phagosomes containing viable tubercle bacilli fail to acidify, apparently because of failure to insert a proton-ATPase pump into the phagosomal membrane [ 4 5 6 ] . This leads to altered vacuolar maturation such that phagosome-lysosome fusion is blocked and the mycobacteria-containing vacuoles end up with an internal pH of about 6 and markers of phagosomes and early and late endosomes [ 7 8 9 10 11 ] . The mycobacterial genes responsible for these processes are largely unknown.

  • This model is consistent with the recent report that MHCK-A displays enrichment into anterior F-actin-rich protrusions of polarized cells during chemotaxis, and into phagocytic and macropinocytotic extensions [ 23 ] . The polar localization of MHCK-A would be consistent with the long-standing "polar relaxation" model for cytoskeletal reorganization during cytokinesis [ 33 ] . MHCK-A may represent a factor that contributes to polar relaxation in this system via polar disassembly of myosin II filaments.

  • Previously, Steimle and colleagues [ 23 ] reported that in interphase cells, during chemotaxis, random migration, and endocytic/phagocytic events, MHCK-A is recruited preferentially to anterior F-actin rich protrusions.

  • Microglia are leukocytes derived outside the central nervous system in the bone marrow, from where they enter the circulation as monocytes and migrate into the brain during late embryonic life establishing permanent residency [ 1 ] . Two different phenotypic forms of microglia are known: the activated but nonphagocytic microglia, which play a role in inflammatory pathologies, and the reactive or phagocytic microglia which participate actively in trauma, infection and neuronal degeneration [ 2 ] .

  • Mutant bacteria with a transposon insertion in prfA (DP-L1075) [ 33] adhere to the host-cell surface, and induce their own uptake into a phagocytic vacuole, presumably through low-level expression of the internalins, but cannot escape from the phagocytic vacuole into the cytoplasm.


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