Example sentences for: pfam

How can you use “pfam” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A curated multiple alignment A from the Pfam database for the protein family that Q belongs to (as determined by hmmpfam from the HMMER package).

  • First, a Pfam family needed to have a significant number of proteins containing no fewer than two TM regions to be identified as a polytopic membrane domain family.

  • (RIO performs a preprocessing step before aligning the query sequence to a Pfam alignment, in which the program hmmsearch is used to trim the query sequence by searching it with the appropriate profile HMM.

  • Pairwise sequence identities within each group range from 24 to 93% for group 1, from 32 to 98% for group 2, and from 45 to 93% for group 3. (Group 1 corresponds to the GCS entry in the Pfam database [ 18].)

  • Using each protein sequence listed in Table 1as a query to search the Conserved Domain Databases, we found that each contained an N-terminal domain with high similarity (BLAST E value < 6 -30) to the ThiF family domain (Pfam00899) (Table 2, Figure 2c), suggesting that this portion of all the proteins in this study performed a similar function.


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