Words similar to perturbation
Example sentences for: perturbation
How can you use “perturbation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Residues that differed in side chain type were constructed using a minimum perturbation (MP) technique [ 24 ] . The MP method changes a given amino acid to the target amino acid preserving the values of equivalent torsion angles between the two side chains, where available.
Indeed, alterations in AVP regulation and secretion are thought to be one possible biochemical abnormality in patients with Obsessive Compulsive Disorder (OCD) [ 15 16 17 18 ] . This disorder is characterized by sudden, recurrent thoughts or images that intrude into consciousness (obsessions) driving stereotyped acts that the person feels compelled to perform (compulsions) [ 19 ] . Interestingly, patients with OCD show elevated basal levels of AVP in the cerebrospinal fluid and exaggerated plasma levels of AVP in response to hypertonic challenge [ 16 ] . Many patients with anorexia nervosa and bulimia nervosa, both compulsive eating disorders, have abnormal levels of AVP in the cerebrospinal fluid and plasma [ 15 17 ] . Pediatric patients with severe OCD have low levels of AVP in cerebrospinal fluid, while a subgroup of pediatric patients with compulsive checking rituals has elevated AVP levels [ 18 ] . Hence, there are many clinical examples of compulsive behavior associated with a perturbation in the AVP system.
The three steps in Figure 1 occur as part of a dynamic equilibrium, and perturbation of any step can shift the equilibrium, leading to transient, partial, or permanent integrin activation/inactivation depending on the extent of perturbation.
An alternative possibility is that they sequester an inactive stockpile of α factor that, upon mutation or signalling by the MEN, is released from these transportins and enables exit from mitosis [ 54 55 ] . Finally, it is possible that the transportin mutants enable bypass through an indirect perturbation of nucleolar architecture (Table 2).
Whole-genome expression profiling exemplified by the development of DNA microarrays represents a major advance in genome-wide functional analysis [ 1 2 ] . In a single assay, the transcriptional response of each gene to a change in cellular state can be measured, whether it is a viral infection, host cell cycle changes, chemical treatment, or genetic perturbation.
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