Example sentences for: perturb

How can you use “perturb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Not only can these factors damage DNA and host tissues but can modulate inflammatory reactions [ 60 ] and stimulate apoptosis [ 64 ] , a major mechanism leading to loss of CD4 +T cells [ 65 ] . TNF-α also has the capacity to perturb the clinical condition in AIDS by strongly upregulating the transcription of the HIV genome [ 66 ] . In fact, it has been proposed [ 67 ] that AIDS is in many ways a TNF-α disease since this cytokine it is a potent activator of NF-kB, and an inducer of HIV genome transcription and apoptosis in HIV-infected T cells.

  • In an unrelated study, we investigated the effects of mefloquine on global transcription in rat neuroblastoma (NG108) cells using microarrays [ 7 ] . Mefloquine caused a striking upregulation of growth arrest and development protein 153 (GADD153), a transcription factor selectively modulated under conditions of ER stress [ 8 ] . Taken together, these observations suggest that mefloquine might perturb the function of the ER via a disruption of calcium homeostasis.

  • Dole is hardly better than Clinton when it comes to the Bill of Rights, and there are lots of Republicans, like Bob Barr of Georgia, who decry only those incursions that perturb the National Rifle Association.

  • neutral-phosphate therapy) is of equal benefit and does not perturb calcium/phosphorus metabolism in children with phosphate-wasting rickets [ 6 ] . Infants with hypercalcemia may have no obvious symptoms, but constitutional symptoms such as poor appetite, irritability, vomiting, FTT, or occasionally seizures may occur [ 7 ] . Classically, hypercalcemia leads to increased urine output and diminished stool frequency.

  • However, not all of the COPII components co-fractionate with NPCs [ 5 6 42 ] . Thus, there are COPII components that perturb GFP-Nup localization that do not co-fractionate with NPCs.


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