Example sentences for: perturb

How can you use “perturb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Instead, when over-expressed in frog or fish embryos, these Wnts perturb the movements of gastrulation.

  • However, not all of the COPII components co-fractionate with NPCs [ 5 6 42 ] . Thus, there are COPII components that perturb GFP-Nup localization that do not co-fractionate with NPCs.

  • Not only can these factors damage DNA and host tissues but can modulate inflammatory reactions [ 60 ] and stimulate apoptosis [ 64 ] , a major mechanism leading to loss of CD4 +T cells [ 65 ] . TNF-α also has the capacity to perturb the clinical condition in AIDS by strongly upregulating the transcription of the HIV genome [ 66 ] . In fact, it has been proposed [ 67 ] that AIDS is in many ways a TNF-α disease since this cytokine it is a potent activator of NF-kB, and an inducer of HIV genome transcription and apoptosis in HIV-infected T cells.

  • MG-132 is a peptide aldehyde that inhibits ubiquitin-mediated proteolysis by binding to and inactivating 20S and 26S proteasomes [ 49 62 ] . Although 1-10 μM MG-132 inhibited first polar body extrusion in rat oocytes, its activity is reversible [ 42 ] . We conducted preliminary experiments to obtain a MG-132 dose range that would transiently perturb or inhibit OM during meiosis I while enabling oocytes to complete OM following washing out of the compound.

  • Rationale for a genetic screen to identify temperature sensitive mutants that perturb NPC assembly and localization


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