Example sentences for: perturb

How can you use “perturb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Instead, when over-expressed in frog or fish embryos, these Wnts perturb the movements of gastrulation.

  • Not only can these factors damage DNA and host tissues but can modulate inflammatory reactions [ 60 ] and stimulate apoptosis [ 64 ] , a major mechanism leading to loss of CD4 +T cells [ 65 ] . TNF-α also has the capacity to perturb the clinical condition in AIDS by strongly upregulating the transcription of the HIV genome [ 66 ] . In fact, it has been proposed [ 67 ] that AIDS is in many ways a TNF-α disease since this cytokine it is a potent activator of NF-kB, and an inducer of HIV genome transcription and apoptosis in HIV-infected T cells.

  • Dole is hardly better than Clinton when it comes to the Bill of Rights, and there are lots of Republicans, like Bob Barr of Georgia, who decry only those incursions that perturb the National Rifle Association.

  • MG-132 is a peptide aldehyde that inhibits ubiquitin-mediated proteolysis by binding to and inactivating 20S and 26S proteasomes [ 49 62 ] . Although 1-10 μM MG-132 inhibited first polar body extrusion in rat oocytes, its activity is reversible [ 42 ] . We conducted preliminary experiments to obtain a MG-132 dose range that would transiently perturb or inhibit OM during meiosis I while enabling oocytes to complete OM following washing out of the compound.

  • In an unrelated study, we investigated the effects of mefloquine on global transcription in rat neuroblastoma (NG108) cells using microarrays [ 7 ] . Mefloquine caused a striking upregulation of growth arrest and development protein 153 (GADD153), a transcription factor selectively modulated under conditions of ER stress [ 8 ] . Taken together, these observations suggest that mefloquine might perturb the function of the ER via a disruption of calcium homeostasis.


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