Words similar to peptidases

Example sentences for: peptidases

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We present a detailed evolutionary and structural analysis of the NlpC/P60 superfamily of peptidases.
By analogy with all other thiol proteases, in the NlpC/P60 superfamily peptidases the cysteine would act as the nucleophile that attacks the peptide bond, while the histidine acts in sequential steps as the base and then acid catalyst for the proton transfers [ 37].
We show that this superfamily, in addition to the well characterized P60-related peptidoglycan peptidases, includes divergent cell-wall hydrolases typified by AcmB/LytN, eukaryotic proteins such as LRAT, Egl-26 and their relatives, amidase domains of GSPSs, and several other uncharacterized bacterial proteins.
Such substitutions have previously been observed in other papain-like peptidases with the serine participating in a functional active site [ 61, 62].
Thiol peptidases of the papain-like, transglutaminase-like, adenoviral protease-like, and caspase-hemoglobinase-like folds have a conserved cysteine (C)-histidine (H) pair [ 29, 30, 31, 32] (Figure 2).